LLM-driven Startups

One way to understand a fast-moving space is to track who's building in it. This is my list of companies creating LLM-driven products in and around healthcare, auto-generated from my research notes.

Focus Area

Agents that handle calls, faxes, and admin that healthcare runs on.

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Agents that understand clinical context, not just admin tasks.

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Company Category Notes Funding Stage Tags
GenHealth AI Other Instead of text, their LLM is being trained on medical events data. Led by 1upHealth founder Ricky Sahu $13M
Triomics Other Oncology-specific model (OncoLLM) to assist with trials, clinical operations $15M Series A
YC
Centaur Labs Infrastructure Data annotation platform, specifically for healthcare $15M
SlingShot AI Other Not much details but the mission of 'task-specific generative models for psychology' is intriguing $30M Seed
OpenEvidence Other First AI to score over 90% on the USMLE. Claim over 100K users $75M Series A
Hippocratic AI Care Navigation Founded 2022 by an experienced team (Munjal Shah, CEO). Pitching a 'safety focused' LLM pre-trained on evidence-based data in healthcare $404M Series C
Thrive AI Health Care Navigation Hyper-personalized AI health coach using Gen AI. OpenAI Startup Fund and Ariana Huffington's Thrive Global $8M Seed
Sully.ai Care Navigation Straight-up AI employees vision (ancillary/support staff like scribes, receptionist, pharmtech, etc). YC'21 $21.8M Series A
YC
Assort Health Workflow Automation Gen AI agents for healthcare call centers, has EHR integrations $3.5M
Laguna Health Workflow Automation Real-time conversational AI incorporating determinants of health $20M+
International
Elise AI Workflow Automation Started with conversational AI products for Housing industry in 2017. Healthcare foray since 2023 for tasks like scheduling, non-clinical communication (mostly in outpatient setting) $140M+
Multi-industry
Tennr Workflow Automation LLM trained as 'document reasoning model' to do eligibility, authorizations, chart creation, referrals etc $18M Series A
Infinitus Workflow Automation Automating provider's phone-based workflows with agents. Applications: eligibility, prior auth, follow-ups $51M Series B
Notable Workflow Automation Auth, referral, scheduling use cases $100M Series B
Latent Health Workflow Automation Applying Gen AI to pharmacy ops (prior auth, 340B qualification) $13M
YC
Mandolin Workflow Automation AI agents built just for specialty drugs workflow (intake, prior auth, RCM) $40M
Autonomize.ai Workflow Automation Prior-auth, Medical Record Review, Care Gaps, etc. So not just ops, billing $32M Series A
TextQL Workflow Automation Multi-industry startup but interesting, explicit healthcare vertical focus $12M
Multi-industry
Hyro Workflow Automation Founded 2018. NY and Israel based $95M
Multi-industryInternational
Attuned Intelligence Workflow Automation Supervised voice agent for healthcare $13M Seed
Syllable Workflow Automation Started with healthcare call center agents but now multi-industry $68M+
Multi-industry
Daffodil Health Revenue Cycle LLM-powered claims repricing for payors $4.6M Seed
Anterior Revenue Cycle Used to be called Co:Helm. Streamlining prior auth using Gen AI $23M Series A
Basys.ai Revenue Cycle Prior Auth solution using Gen AI. ?Acquired? $2.4M Seed
Humata Revenue Cycle Prior Auth $25M
Machinify Revenue Cycle GenAI-driven healthcare ops in three areas: 1. Claim Audit, 2. Billing Review, 3. Prior Auth (sold to Evolent Health in June 2024!) $12M Series A
Risa Revenue Cycle Prior auth focused on oncology $3.5M Seed
PenguinAI Revenue Cycle RCM-focused AI agents. Optum/UHG team $25M Series A
Ambience Healthcare Documentation AI-Scribe solutions $106M
Nabla Documentation Notably has Yann LeCun as advisor $44M
International
Abridge Documentation GenAI ambient scribe; enterprise leader across major health systems. a16z-led, $5.3B valuation. $778M Series E
Pieces Documentation Chart summarization, progress note drafting, billing aids $61M
Navina Documentation Summaries for chart review, risk adjustment, diagnostic decision support $44M
HealthSage Documentation Vision is to be a Gen AI 'platform'. Current application is LLM-based conversion of clinical note to FHIR €3M Seed
International
Tortus Documentation Clinical documentation scribe $4.2M Seed
Lassie Workflow Automation Front/back-office agents for small dental practices - reads claims, reconciles payments, posts to the ledger. A16z led the $35M A in Jun 2026. Might be targeting medical offices as well. $47M Series A
Trase Workflow Automation Agent for regulated industries - healthcare included. Duke cardiology deployment. Huge $107M seed (by ARCH, Red Cell) is a statement. $117.5M Seed
Multi-industry
Amperos Health Revenue Cycle 'Amanda,' an AI biller that works denials and collections end-to-end. Bessemer-led $16M A (Jun 2026). $20M Series A
Prosper AI Revenue Cycle Voice agents for patient access and RCM calls (eligibility, prior-auth status, etc). a16z-led $30M A. $30M Series A
Freed Documentation AI Scribe for SMB sector (independent/outpatient clinicians). Sequoia-led $30M A; founded by an ex-Meta engineer. $34M Series A
Doctronic Care Navigation Founded 2023. Consumer-facing "AI doctor": an LLM agent runs symptom intake and makes clinical decisions before handing off to a telehealth clinician for $39. In Jan 2026 Utah made it the first AI cleared to legally renew prescriptions for chronic conditions. $65M Series B
Qualified Health Infrastructure Governance and observability layer for health systems to deploy and monitor genAI agents across clinical and admin workflows, not a point app. NEA-led $125M Series B; Anthropic also invested (Mar 2026). $155M Series B
Nitra Workflow Automation Healthcare fintech (Visa spend card, payments) that rebranded an 'AI-native OS' in 2024, now running LLM agents for vendor procurement and voice scheduling/eligibility; the fintech core predates the AI layer. $90M Series B
Develop Health Revenue Cycle LLM pipelines purpose-built for prior auth workflow of medications. Founded 2022, priced Series A. $17.6M Series A
Layer Health Infrastructure Founded 2023, MIT spin-out. LLM platform trained on longitudinal patient data to do chart abstraction for quality, registries, and research (not ambient scribing). $21M Series A in Mar 2025 led by Define Ventures (GV, Flare, MultiCare). $25M Series A
Voize Documentation Founded 2020, Berlin. Nursing documentation done locally on a phone, without constant connectivity. 75K+ nurses across 1,100+ German/Austrian facilities. $50M Series A, now expanding to the US. $50M Series A
InternationalYC
Amigo AI Care Navigation Patient and provider-facing clinical LLM agents. $11M Series A, Optum Ventures, Mar 2026. $17M Series A
Insight Health Workflow Automation Voice + chat LLM agents for routine clinical admin (intake/screening, referrals, pre-auth, fax) plus ambient scribe. $11M Series A. $15.6M Series A
Health Universe Infrastructure Platform for auditable AI agents in regulated healthcare workflows (oncology, clinical trials). Founded 2023, SF; $6M seed led by Kleiner Perkins. $9.5M Seed
Foundation Health Revenue Cycle Pharmacy prior-auth agent (PAIGE) drafts payer question responses + appeal letters using LLMs fine-tuned for pharmacy. Founder Umar Afridi ran Truepill 2016-22. $20M Series A led by Define Ventures. $26M Series A
Basata.ai Workflow Automation Fax-in specialist referral to AI voice agent: extracts data, auto-charts in EHR, calls the patient to book. Founded ~2024, $21M Series A. $24.5M Series A
Confido Health Workflow Automation Voice AI agents run the practice front desk end-to-end (scheduling, refills, payments, EHR writeback) on a "fully generative multi-agent" platform. $10M Series A. $13M Series A
Elicit Other General-purpose LLM research tool with a genuine pharma/medtech vertical. $31M Series A
Multi-industry
Vega Health Infrastructure A marketplace that vets/distributes other companies' traditional predictive-ML models (Sepsis Watch, PCCI risk models). $4M seed from Bessemer. $4M Seed
Knit Health Infrastructure UC Berkeley spinout, $11.6M seed (Uncork + Frist Cressey, May 2026) building a "Large Clinical Behavior Model" on Truveta data from 130M+ patients. $11.6M Seed