Digital Medicine

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With Regulatory Approvals

  • Pear Therapeutics: Interesting approach of using barcode on med-packaging to deliver digital care management packages. Since 2013. $20M raised. Opioid Addiction product going through approval.
  • Dthera Sciences: Alzhiemer's product undergoing approval at FDA. Front-facing camera of custom tablet captures emotional response to family photos and uses AI to adjust content.
  • Cognoa: Machine learning app for pediatric behavioral health. Has received categorization from the FDA as a diagnostic medical device for autism. $20M+ raised. Palo alto.
  • Click Therapeutics: $25M+ from Sanofi, Flatiron. Undergoing FDA clearance for Depression offering (first in pipeline).
  • Voluntis: French based. Raised $31M+. IPO'd May'18. CE and FDA approved for Diabetes Digital Therapeutic. Partnership with Roche, Abbview, AZ, Sanofi. Other areas: Oncology, Coagulation, Hemophilia.


  • Mindmaze: Swiss-based. $108M raised. VR and 3D motion capture based on neuroscience protocols, for brain injury patients. CE mark in Europe.
  • Psious: VR for psychiatry. Barcelona-based. Early stage.
  • Limbix: VR for psychiatry. SF-based. Early stage.
  • AppliedVR: VR for pain and anxiety management. Unknown funding.
  • VirtuallyBetter: Quasi-academic team creating VR packages for behavioral health. Unknown funding.
  • Surgical Theater: VR platform for pre-surgery planning, reharsal and patient education.$9.6M raised.
  • Vicarious Surgical: Stealth mode, but focused on VR+Surgery. At least $2.4M raised.
  • EchoPixel: Patient-specific anatomy in VR. $8.5M. Mountain View.
  • GibLib: Online subscription for curated and original content of surgeries. $1M raised.
  • Level Ex: AR, VR, Video games for surgical training. CME credits. $13M raised.


  • Reflexion Health: $29M raised. Kinect-based physical therapy. FDA approved in late 2015. West Health spinoff.
  • Jintronix: $6M raised. Montreal-based. Same as Reflexion. Got FDA approved in early 2015.
  • BioGaming: Israeli competitor to Reflexion. Raised $3.8M. FDA approved in early 2016.
  • ClarisReflex: Post op monitoring for knee replacement patients. Unknown funding.
  • Physera: Acquired by Omada Health in 2020.
  • HingeHealth: $130M, BVP
  • FocusMotion: Orthopedic recovery. $270 pre-seed funded. Cedars-Sinai Accelerator.
  • Kiio: $13.8M raised. Wisconsin. MSK care focused.

D2C Lab Tests


  • Smartphone-based urinalysis. Israel. $12M Series A.
  • Click Therapeutics: $23M raised. Digital therapeutics. Smoking cessation product launched. Sanofi as lead investor!
  • Akili Video game that aims to do cognitive therapeutics, assessments, and diagnostics
  • [ Wheel]: Interesting staffing marketplace for virtual care companies to find clinician workforce. $13.9M Series A with CRV. Austin, TX.